nmronline, to nauka
@nmronline@mstdn.science avatar
bibliolater, to nauka
@bibliolater@qoto.org avatar

"Y-chromosome results highlight a significant genetic differentiation between the North-Western and South-Eastern part of the Mediterranean, the Italian Peninsula occupying an intermediate position therein. In particular, Sicily and Southern Italy reveal a shared paternal genetic background with the Balkan Peninsula and the time estimates of main Y-chromosome lineages signal paternal genetic traces of Neolithic and post-Neolithic migration events."

Sarno S, Boattini A, Carta M, Ferri G, Alù M, et al. (2014) An Ancient Mediterranean Melting Pot: Investigating the Uniparental Genetic Structure and Population History of Sicily and Southern Italy. PLOS ONE 9(4): e96074. https://doi.org/10.1371/journal.pone.0096074 @science @biology @anthropology

nmronline, to nauka
@nmronline@mstdn.science avatar
nmronline, to nauka
@nmronline@mstdn.science avatar

3 years ago today, we began Tweeting updates about our little hobby project.

It's hard to believe that what started as a lockdown activity, has grown to where we are now.

Life changing.

Thank you for following our journey, and get ready to GO ELECTRO (and more) in 2024!

@bioinformatics @biophysics @chemistry @compchem @nmrchat @physics @strucbio

bibliolater, to nauka
@bibliolater@qoto.org avatar

"Just 300,000 years ago – a blink in evolutionary time – at least nine species of humans wandered the planet. Today, only our own, Homo sapiens, remains. And this raises one of the biggest questions in the story of human evolution: where did everyone else go?" https://www.theguardian.com/science/2023/nov/18/where-did-other-human-species-go-vanished-ancestors-homo-sapiens-neanderthals-denisovans @science

nmronline, to nauka
@nmronline@mstdn.science avatar

Should we include intrinsically disordered proteins (IDPs) software in the – ELECTRO library?

If so, what software, and/or what functionality, do you recommend?

@bioinformatics @biophysics @chemistry @compchem @nmrchat @physics @strucbio

nmronline, to nauka
@nmronline@mstdn.science avatar
nmronline, to nauka
@nmronline@mstdn.science avatar
nmronline, to art
@nmronline@mstdn.science avatar
nmronline, to art
@nmronline@mstdn.science avatar
nmronline, to art
@nmronline@mstdn.science avatar
bibliolater, to nauka
@bibliolater@qoto.org avatar

Engineered yeast breaks new record: a genome with over 50% synthetic DNA https://www.nature.com/articles/d41586-023-03495-4 @science @biology

8petros, to nauka

Like all other bacteria, cyanobacteria has different genetic circuits, which tell the cells what outputs to produce. Our team genetically engineered the bacterial DNA so that the cells created a specific enzyme called laccase.

The laccase enzyme produced by the cyanobacteria works by performing a chemical reaction with a pollutant that transforms it into a form that’s no longer functional. By breaking the chemical bonds, it can make a toxic pollutant nontoxic. The enzyme is regenerated at the end of the reaction, and it goes off to complete more reactions.

Once we’d embedded these laccase-creating cyanobacteria into the alginate hydrogel, we put them in a solution made up of industrial dye pollutant to see if they could clean up the dye. In this test, we wanted to see if our material could change the structure of the dye so that it went from being colored to uncolored. But, in other cases, the material could potentially change a chemical structure to go from toxic to nontoxic.

Engineered 'living materials' could help clean up water pollution one day

nmronline, to nauka
@nmronline@mstdn.science avatar
bibliolater, to nauka
@bibliolater@qoto.org avatar

🇮🇷 "The results show an autochthonous but non-homogeneous ancient background mainly composed by J2a sub-clades with different external contributions. The phylogeography of the main haplogroups allowed identifying post-glacial and Neolithic expansions toward western Eurasia but also recent movements towards the Iranian region from western Eurasia (R1b-L23), Central Asia (Q-M25), Asia Minor (J2a-M92) and southern Mesopotamia (J1-Page08)."

Grugni V, Battaglia V, Hooshiar Kashani B, Parolo S, Al-Zahery N, et al. (2012) Ancient Migratory Events in the Middle East: New Clues from the Y-Chromosome Variation of Modern Iranians. PLOS ONE 7(7): e41252. https://doi.org/10.1371/journal.pone.0041252 @science

bibliolater, to nauka
@bibliolater@qoto.org avatar

"We present 14 new ancient mitogenome sequences from pre-Phoenician (~1800 BCE) and Phoenician (~700–400 BCE) samples from Lebanon (n = 4) and Sardinia (n = 10) and compare these with 87 new complete mitogenomes from modern Lebanese and 21 recently published pre-Phoenician ancient mitogenomes from Sardinia to investigate the population dynamics of the Phoenician (Punic) site of Monte Sirai, in southern Sardinia."

Matisoo-Smith E, Gosling AL, Platt D, Kardailsky O, Prost S, et al. (2018) Ancient mitogenomes of Phoenicians from Sardinia and Lebanon: A story of settlement, integration, and female mobility. PLOS ONE 13(1): e0190169. https://doi.org/10.1371/journal.pone.0190169 @science

: https://doi.org/10.1371/journal.pone.0190169.g001

nmronline, to fediverse
@nmronline@mstdn.science avatar

Hi everyone,

We have just noticed that the majority of our Following list was reset on .

We have refollowed everyone who is following us, so hopefully that has resolved the issue.

@bioinformatics @biophysics @chemistry @compchem @nmrchat @physics @strucbio


bibliolater, to nauka
@bibliolater@qoto.org avatar

"We have combined a detailed, high-resolution mitogenome analysis with summaries of autosomal data and Y-chromosome lineages to establish a settlement chronology for the Indian Subcontinent."

Silva, M., Oliveira, M., Vieira, D. et al. A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals. BMC Evol Biol 17, 88 (2017). https://doi.org/10.1186/s12862-017-0936-9 @science

nmronline, to nauka
@nmronline@mstdn.science avatar
bibliolater, to nauka
@bibliolater@qoto.org avatar

"In the context of European populations, and particularly in Iberia, this haplogroup stands out for its high frequency and its demographic history. Current evidence indicates that the diffusion of this haplogroup is related to the population movements that mark the cultural Bronze Age transition, making it remarkably interesting for population geneticists."

García-Fernández, C., Lizano, E., Telford, M. et al. Y-chromosome target enrichment reveals rapid expansion of haplogroup R1b-DF27 in Iberia during the Bronze Age transition. Sci Rep 12, 20708 (2022). https://doi.org/10.1038/s41598-022-25200-7 @science @anthropology

bibliolater, to nauka
@bibliolater@qoto.org avatar

"Our study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia."

Hofmanová, Z. et al. (2016) 'Early farmers from across Europe directly descended from Neolithic Aegeans,' Proceedings of the National Academy of Sciences of the United States of America, 113(25), pp. 6886–6891. https://doi.org/10.1073/pnas.1523951113. @anthropology @science @archaeodons

bibliolater, to nauka
@bibliolater@qoto.org avatar

"We analyzed a comprehensive autosomal and Y-chromosome dataset of Eurasian and African populations identifying genetic signals of regional LGP population isolation, and contrasted expansion time estimates and dispersal routes in the region with archaeological, palaeontological, palaeobotanical, and climate data."

Platt, D., Haber, M., Dagher-Kharrat, M. et al. Mapping Post-Glacial expansions: The Peopling of Southwest Asia. Sci Rep 7, 40338 (2017). https://doi.org/10.1038/srep40338 @science @archaeodons

nmronline, to nauka
@nmronline@mstdn.science avatar
nmronline, to AI
@nmronline@mstdn.science avatar
Impossible_PhD, to lgbt
@Impossible_PhD@hachyderm.io avatar

You've probably heard from transphobes about how "you can't change your DNA," so nothing you do in transition really matters. "Basic biology," they whinge. Well... what about intermediate biology?

This week on , come and see How HRT Rewrites Your DNA by just plain turning off the parts you don't need and turning on the ones you do! Now with more wedding photos, from another queer wedding.

https://stainedglasswoman.substack.com/p/how-hrt-rewrites-your-dna

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